Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Genes that deregulate mTOR signaling as candidates for autism spectrum disorders  

Tuberous Sclerosis Complex (TSC) genes regulate signaling mediated through mammalian target of rapamycin, referred to as mTOR. mTOR signaling plays an essential role in determining how neurons in brain communicate with each other. This project will test whether genes that control mTOR signaling are associated with an increased risk for autism spectrum disorders.

2008

Funder National Institutes of Health
Fiscal Year Funding $196,875.00
Project Number R21MH079213-02
Principal Investigator Ramesh, Vijaya
Strategic Plan Question Question 3: What Caused This To Happen And Can This Be Prevented? (Risk Factors)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 3.8 Identify genetic risk factors in at least 50% of people with ASD by 2014. IACC Recommended Budget: $33,900,000 over 6 years.
Federal or Private? Federal
Institution Massachusetts General Hospital
State/Country Massachusetts
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