Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Early pharmacologic intervention in autism: Fluoxetine in preschool children  

This is a revised protocol examining the impact of sustained early pharmacologic intervention in preschool children with autism. Young (30-58 months) children with narrowly defined autism will be randomly assigned to yearlong treatment with placebo or fluoxetine, a selective serotonin reuptake inhibitor (SSRI) which is approved for other indications in children as young as six years. The primary outcome measure will be the pattern of development in behavioral domains that appear particularly compromised in autism: specifically reciprocal social interaction, pragmatic communication, and restricted interests and/or repetitive behaviors.


Funder National Institutes of Health
Fiscal Year Funding $1,712.00
Project Number M01RR000071-45
Principal Investigator Hollander, Eric
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4.4 Launch three randomized controlled trials of interventions for school-aged and/or adolescents by 2012. IACC Recommended Budget: $15,600,000 over 5 years.
Federal or Private? Federal
Institution Mount Sinai School of Medicine
State/Country New York
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Not available at this time. This functionality is experimental.