Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Regulation of MET expression in autism disorder and forebrain ontogeny  

First, this study aims to determine the transcriptional regulators of a functional variant in the human MET promoter that is associated with autism spectrum disorder (ASD) vulnerability. Second, the study will define the mechanisms through which the mouse Met receptor tyrosine kinase influences forebrain ontogeny.


Funder National Institutes of Health
Fiscal Year Funding $25,583.00
Project Number F30MH083474-02
Principal Investigator Bergman, Mica
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4.5 Standardize and validate at least 20 model systems (e.g. cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution Vanderbilt University
State/Country Tennessee
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Regulation of MET expression in autism disorder and forebrain ontogeny | $25,800.00 | 2009 | 5F30MH083474-03