Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Neocortical regionalization: Analysis of genetic and epigenetic influences  

The proposed research will directly examine the influence of input, gene expression and their interactions on neocortical regionalization, and how these interactional influences vary by developmental maturity. Many pervasive developmental disorders (PDD) in children are caused by abnormal brain development that occurs during the time when higher-level brain centers, such as those within the neocortex, are developing.


Funder National Institutes of Health
Fiscal Year Funding $75,000.00
Project Number R03MH080502-01A1
Principal Investigator Huffman, Kelly
Strategic Plan Question Question 4: Which Treatments And Interventions Will Help? (Interventions)
Strategic Plan Objective Green dot: Objective has greater than or equal to the recommended funding. 4.5 Standardize and validate at least 20 model systems (e.g. cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years.
Federal or Private? Federal
Institution University of California, Riverside
State/Country California
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
New! History/Related Projects Neocortical regionalization: Analysis of genetic and epigenetic influences | $75,000.00 | 2009 | 5R03MH080502-02