Project Detail
Interagency Autism Coordinating Committee (IACC) logo
Office of Autism Research Coordination (OARC) logo

Exploring the role of synaptic proteins in mouse models of autism  

Brian Chait and his team at the Rockefeller University specialize in using mass spectrometry and other powerful biochemical tools to study the structure and function of proteins and protein assemblies. Chait is assisting his colleague Paul Greengard in examining changes in protein phosphorylation in mice given anti-psychotic drugs. Chait is also working with his colleague Nathaniel Heintz in sorting out, for the first time, the protein compositions of synapses making connections between specific types of neurons in the mouse brain. These techniques could provide valuable information on how autism changes the molecular machinery of brain cells.


Funder Simons Foundation
Fiscal Year Funding $66,228.00
Project Number Project number unavailable
Principal Investigator Chait, Brian
Strategic Plan Question Question 2: How Can I Understand What Is Happening? (Biology)
Strategic Plan Objective 2O. Not specific to Question 2 objectives
Federal or Private? Private
Institution The Rockefeller University
State/Country New York
Web Link 1 No URL available.
Web Link 2 No URL available.
Web Link 3 No URL available.
History/Related Projects Exploring the role of synaptic proteins in mouse models of autism | $165,572.00 | 2008 | Project number unavailable