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Strategic Plan Cover

IACC Strategic Plan

For Autism Spectrum Disorder Research

2011 Update

Appendices

References

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Chowdhury M, Benson B, Hillier A. Changes in restricted repetitive behaviors with age: a study of high-functioning adults with autism spectrum disorders. Res Autism Spectr Disord. April-June 2010;4(2):210-216.

Cohen IL, Tsiouris JA, Flory MJ, Kim SY, Freedland R, Heaney G, Pettinger J, Ted-Brown W. A large-scale study of the psychometric characteristics of IBR modified overt aggression scale: findings and evidence for increased self-destructive behaviors in adult females with autism spectrum disorder. J Autism Dev Disord. 2010 May;40(5):599-609. [PMID: 19941156]

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Durand CM, Betancur C, Boeckers TM, Bockmann J, Chaste P, Fauchereau F, Nygren G, Rastam M, Gillberg IC, Anckarsäter H, Sponheim E, Goubran-Botros H, Delorme R, Chabane N, Mouren-Simeoni MC, de Mas P, Bieth E, Rogé B, Héron D, Burglen L, Gillberg C, Leboyer M, Bourgeron T. Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet. 2007 Jan;39(1):25-7. [PMID: 17173049]

Dziobek I, Bahnemann M, Convit A, Heekeren HR. The role of the fusiform-amygdala system in the pathophysiology of autism. Arch Gen Psychiatry. 2010 Apr;67(4):397-405. [PMID: 20368515]

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Esbensen AJ, Bishop S, Seltzer MM, Greenberg JS, Taylor JL. Comparisons between individuals with autism spectrum disorders and individuals with Down Syndrome in adulthood. Am J Intellect Dev Disabil. 2010 July;115(4):277-90. [PMID: 20563296]

Esbensen AJ, Greenberg J, Seltzer MM, Aman MG. A longitudinal investigation of psychotropic and non-psychotropic medication use among adolescents and adults with autism spectrum disorders. J Autism Dev Disord. 2009 September;39(9):1339-1349. [PMID: 19434487]

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Eskenazi B, Marks AR, Bradman A, Harley K, Barr DB, Johnson C, Morga N, Jewell NP. Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environ Health Perspect. 2007 May;115(5):792-8. [PMID: 17520070]

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Frankel F, Myatt R, Sugar C, Whitham C, Gorospe CM, Laugeson E. A randomized controlled study of parent-assisted Children's Friendship Training with children having autism spectrum disorders. J Autism Dev Disord. 2010 July;40(7):827-42. [PMID: 20058059]

Frazier TW, Youngstrom EA, Haycook T, Sinoff A, Dimitriou F, Knapp J, Sinclair L. Effectiveness of medication combined with intensive behavioral intervention for reducing aggression in youth with autism spectrum disorder. J Child Adolesc Psychopharmacol. 2010 Jun; 20(3):167-77. [PMID: 20578929]

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Giarelli E, Wiggins LD, Rice CE, Levy SE, Kirby RS, Pinto-Martin J, Mandell D. Sex differences in the evaluation and diagnosis of autism spectrum disorders among children. Disabil Health J. 2010 Apr;3(2):107-116. [PMID: 2122776]

Gillberg C, Billstedt E, Sundah V, Gillberg IC. Mortality in autism: a prospective longitudinal community-based study. J Autism Dev Disord. 2010 Mar;40(3):352-7. [PMID: 19838782]

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Grether JK, Anderson MC, Croen LA, Smith D, Windham GC. Risk of autism and increasing maternal and paternal age in a large North American population. Am J Epidemiol. 2009 Nov 1; 170(9):1118-1126. [PMID: 19783586]

Groen W, Teluij M, Buitelaar J, Tendolkar I. Amygdala and hippocampus enlargement during adolescence in autism. J Am Acad Child Adolesc Psychiatry. 2010 Jun;49(6):552-60. [PMID: 20494265]

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Hamilton SM, Spencer CM, Harrison WR, Yuva-Paylor LA, Graham DF, Daza RA, Hevner R, Overbeek PA, Paylor R. Multiple autism-like behaviors in a novel transgenic mouse model. Behav Brain Res. 2011;218:29-41. [PMID: 21093492]

Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Gilmore J, Piven J. Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years. Arch Gen Psychiatry. 2005 Dec;62(12):1366-1376. [PMID: 16330725]

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Hertz-Picciotto I, Delwiche L. The rise of autism and the role of age at diagnosis. Epidemiology. 2009 Jan;20(1):84-90. [PMID: 19307110]

Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. Blood mercury concentrations in CHARGE Study children with and without autism. Environ Health Perspect. 2010 Jan;118(1):161-6. [PMID: 20056569]

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Hove O, Havik OE. Developmental level and other factors associated with symptoms of mental disorders and problem behaviour in adults with intellectual disabilities living in the community. Soc Psychiatry Psychiatr Epidemiol. 2010 Jan;45(1):105-13. [PMID: 19347237]

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Interagency Autism Coordinating Committee (IACC). 2009 IACC Autism Spectrum Disorder Research Portfolio Analysis Report (Draft). (PDF – 1.7 MB) 2010 Oct 22.

Institute of Educational Sciences, U.S. Department of Education. Early Childhood Education Intervention for Children with Disabilities: Lovaas Model of Applied Behavior Analysis, August 2010.

Jamain S, Quach H, Betancur C, Råstam M, Colineaux C, Gillberg IC, Soderstrom H, Giros B, Leboyer M, Gillberg C, Bourgeron T. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet. 2003 May;34(1):27-9. [PMID: 12669065]

Järbrink K, Fombonne E, Knapp M. Measuring the parental, service and cost impacts of children with autistic spectrum disorder: a pilot study. J Autism Dev Disord. 2003; 33(4), 395-402. [PMID: 12959418]

Johnson N, Oliff P, Williams E. An update on state budget cuts. (PDF – 751 KB) Center on Budget and Policy Priorities. 2010 Nov 5.

Johnson S, Hollis C, Kochhar P, Hennessey E, Wolke D, Marlow N. Autism spectrum disorders in extremely preterm children. J Pediatr. 2010 Apr;156(4):525-31.e2. [PMID: 20056232]

Kaiser MD, Delmolino L, Tanaka JW, Shiffrar M. Comparison of visual sensitivity to human and object motion in autism spectrum disorder. Autism Res. 2010 Aug;3(4):191-5. [PMID: 20533450]

Kaiser MD, Hudac CM, Shultz S, Lee SM, Cheung C, Berken AM, Deen B, Pitskel NB, Sugrue DR, Voos AC, Saulnier CA, Ventola P, Wolf JM, Klin A, Vander Wyk BC, Pelphrey KA. Neural signatures of autism. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21223-8. [PMID: 21078973]

Kasari C, Gulsrud AC, Wong C, Kwon S, Locke J. Randomized controlled caregiver mediated joint engagement intervention for toddlers with autism. J Autism Dev Disord. 2010 Sep;40(9):1045-56. [PMID: 20145986]

Kikuchi Y, Senju A, Akechi H, Tojo Y, Osanai H, Hasegawa T. Atypical disengagement from faces and its modulation by the control of eye fixation in children with autism spectrum disorder. J Autism Dev Disord. 2010 Aug 17. [Epub ahead of print] [PMID: 20714799]

King BH, Hollander E, Sikich L, McCracken JT, Scahill L, Bregman JD, Donnelly CL, Anagnostou E, Dukes K, Sullivan L, Hirtz D, Wagner A, Ritz L. Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism. Arch Gen Psychiatry. 2009 Jun;66(6):583-90. [PMID: 19487623]

King M, Bearman P. Diagnostic change and the increased prevalence of autism. Int J Epidemiol. 2009 Oct;38(5):1224-34. [PMID: 19737791]

King TM, Tandon SD, Macias MM, Healy JA, Duncan PM, Swigonski NL, Skipper SM, Lipkin PH. Implementing developmental screening and referrals: lessons learned from a national project. Pediatrics. 2010 Feb;125(2):350-60. [PMID: 20100754]

Kliemann D, Dziobek I, Hatri A, Steimke R, Heekeren HR. Atypical reflexive gaze patterns on emotional faces in autism spectrum disorders. J Neurosci. 2010 Sep 15;30(37):12281-7. [PMID: 20844124]

Klin A, Lin DJ, Gorrindo P, Ramsay G, Jones W. Two-year olds with autism orient to non-social contingencies rather than biological motion. Nature. 2009 May 14; 459(7244):257-261. [PMID: 19329996]

Knapp M, Romeo R, Beechum J. Economic cost of autism in the UK. Autism. 2009 May;13(3):317-336. [PMID: 19369391]

Kogan MD, Blumberg SJ, Schieve LA, Boyle CA, Perrin JM, Ghandour RM, Singh GK, Strickland BB, Trevathan E, van Dyck PC. Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics. 2009 Nov;124(5):1395-403. [PMID: 19805460]

Koh HC, Milne E, Dobkins K. Contrast sensitivity for motion detection and direction discrimination in adolescents with autism spectrum disorders and their siblings. Neuropsychologia. 2010 Dec;48(14):4046-56. [PMID: 20937290]

Kolevzon A, Mathewson KA, Hollander E. Selective serotonin reuptake inhibitors in autism: a review of efficacy and tolerability. J Clin Psychiatry. 2006 Mar; 67(3):407-14. [PMID: 16649827]

Krauss M, Gulley S, Sciegaj M, Wells N. Access to specialty medical care for children with mental retardation, autism and other special health care needs. Ment Retard. 2003;41(5):329-339. [PMID: 12962535]

Kumar A, Sundaram SK, Sivaswamy L, Behen ME, Makki MI, Ager J, Janisse J, Chugani HT, Chugani DC. Alterations in frontal lobe tracts and corpus callosum in young children with autism spectrum disorder. Cereb Cortex. 2010 Sep;20(9):2103-13. [PMID: 20019145]

Kumar RA, KaraMohamed S, Sudi J, Conrad DF, Brune C, Badner JA, Gilliam TC, Nowak NJ, Cook EH Jr, Dobyns WB, Christian SL. Recurrent 16p11.2 microdeletions in autism. Hum Mol Genet. 2008 Feb 15;17(4):628-38. [PMID: 18156158]

Lai MC, Lombardo MV, Chakrabarti B, Sadek SA, Pasco G, Wheelwright SJ, Bullmore ET, Baron-Cohen S; MRC AIMS Consortium, Suckling J. A shift to randomness of brain oscillations in people with autism. Biol Psychiatry. 2010 Dec 15;68(12):1092-9. [PMID: 20728872]

Landa RJ, Holman KC, Garrett-Mayer E. Social and communication development in toddlers with early and later diagnosis of autism spectrum disorders. Arch Gen Psychiatry. 2007 Jul;64(7):853-64. [PMID: 17606819]

Lang R, Regester A, Lauderdale S, Ashbaugh K, Haring A. Treatment of anxiety in autism spectrum disorders using cognitive behaviour therapy: A systematic review. Dev Neurorehabil. 2010 Feb;13(1):53-63. [PMID: 20067346]

Laumonnier F, Bonnet-Brilhault F, Gomot M, Blanc R, David A, Moizard MP, Raynaud M, Ronce N, Lemonnier E, Calvas P, Laudier B, Chelly J, Fryns JP, Ropers HH, Hamel BC, Andres C, Barthélémy C, Moraine C, Briault S. X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family. Am J Hum Genet. 2004 Mar;74(3):552-7. [PMID: 14963808]

Levy SE, Hyman SL. Use of complementary and alternative treatments for children with autistic spectrum disorders is increasing. Pediatr Ann. 2003 Oct;32(10):685-91. [PMID: 14606219]

Lintas C, Altieri L, Lombardi F, Sacco R, Persico AM. Association of autism with polyomavirus infection in postmortem brains. J Neurovirol. 2010 Apr;16(2):141-9. [PMID: 20345322]

Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, Ecker JR. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 2009 Nov 19;462(7271):315-22. [PMID: 19829295]

Loo CY, Graham RM, Hughes CV. Behaviour guidance in dental treatment of patients with autism spectrum disorder. Int J Paediat Dent. 2009 Nov;19(6):390-8. [PMID: 19619200]

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Loth E, Gómez JC, Happé F. When seeing depends on knowing: adults with Autism Spectrum Conditions show diminished top-down processes in the visual perception of degraded faces but not degraded objects. Neuropsychologia. 2010 Apr;48(5):1227-36. [PMID: 20026140]

Mandell D, Palmer R. Differences among states in the identification of autistic spectrum disorders. Arch Pediatr Adolesc Med. 2005 Mar; 159(3):266-269. [PMID: 15753271]

Mandell D, Morales K, Marcus S, Stahmer A, Doshi J, Polsky D. Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics. 2008 Mar; 121(3):e441-448. [PMID: 18310165]

Mandell DS, Ittenbach RF, Levy SE, Pinto-Martin JA. Disparities in diagnosis received prior to a diagnosis of autism spectrum disorder. J Autism Dev Disord. 2007 Oct; 37(9):1795-1802. [PMID: 17160456]

Marshall CR, Noor A, Vincent JB, Lionel AC, Feuk L, Skaug J, Shago M, Moessner R, Pinto D, Ren Y, Thiruvahindrapduram B, Fiebig A, Schreiber S, Friedman J, Ketelaars CEJ, Vos YJ, Ficicioglu C, Kirkpatrick S, Nicolson R, Sloman L, Summers A, Gibbons CA, Teebi A, Chitayat D, Weksberg R, Thompson A, Vardy C, Crosbie V, Luscombe S, Baatjes R, Zwaigenbaum L, Roberts W, Fernandez B, Szatmari P, Scherer SW. Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet. 2008 Feb;82(2):477-488. [PMID: 18252227]

Mazumdar S, King M, Liu KY, Zerubavel N, Bearman P. The spatial structure of autism in California, 1993-2001. Health Place. 2010 May;16(3):539-46. [PMID: 20097113]

McClannahan LE, MacDuff GS, Krantz PJ. Behavior analysis and intervention for adults with autism. Behav Modif. 2002 Jan;26(1):9-26. [PMID: 11799656]

McDonough JT, Revell G. Accessing employment supports in the adult system for transitioning youth with autism spectrum disorders. J Vocational Rehab. 2010 Apr;32:89-100.

McDougle CJ, Scahill L, Aman MG, McCracken JT, Tierney E, Davies M, Arnold LE, Posey DJ, Martin A, Ghuman JK, Shah B, Chuang SZ, Swiezy NB, Gonzalez NM, Hollway J, Koenig K, McGough JJ, Ritz L, Vitiello B. Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. Am J Psychiatry. 2005 Jun;162(6):1142-8. [PMID: 15930063]

McVicar KA, Ballaban-Gil K, Rapin I, Moshé SL, Shinnar S. Epileptiform EEG abnormalities in children with language regression. Neurology. 2005 Jul;65(1):129-31. [PMID: 16009899]

Mehler MF, Purpura DP. Autism, fever, epigenetics and the locus coeruleus. Brain Res Rev. 2009 Mar;59(2):388-92. [PMID: 19059284]

Miller DT, Adam MP, Aradhya S, Biesecker LG, Brothman AR, Carter NP, Church DM, Crolla JA, Eichler EE, Epstein CJ, Faucett WA, Feuk L, Friedman JM, Hamosh A, Jackson L, Kaminsky EB, Kok K, Krantz ID, Kuhn RM, Lee C, Ostell JM, Rosenberg C, Scherer SW, Spinner NB, Stavropoulos DJ, Tepperberg JH, Thorland EC, Vermeesch JR, Waggoner DJ, Watson MS, Martin CL, Ledbetter DH. Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies. Am J Hum Genet. 2010 May 14;86(5):749-64. [PMID: 20466091]

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About the IACC

The Interagency Autism Coordinating Committee (IACC) was established by Congress under the Combating Autism Act of 2006 (CAA) to provide advice to the Secretary of Health and Human Services (HHS) and coordinate all efforts within HHS concerning autism spectrum disorders (ASD).

As mandated by law, the IACC has a membership composed of Federal officials from agencies involved in autism research and services and public members, including people with ASD, parents of children and adults with ASD, and members of the autism advocacy and research community. The diversity of the Committee ensures that a broad range of views and opinions is reflected and discussed in a public forum.

Under the CAA, the IACC is required to (1) develop and annually update a Strategic Plan for ASD research, (2) develop and annually update a summary of advances in ASD research, and (3) monitor federal activities related to ASD.

In developing and updating the IACC Strategic Plan for Autism Spectrum Disorder Research since it was first released in 2009, the IACC has laid out a framework for the pursuit of critical biomedical and services research. Through activities such as public meetings and workshops, publication of an annual Summary of Advances in ASD Research, dissemination of information regarding ASD research and IACC activities, gathering of public input and coordination of Federal activities related to autism, the IACC continues in its effort to provide guidance to the Department of Health and Human Services and to reach out to the broader autism community to find ways to work together to help people with autism and their families.

IACC Member Roster

Chair

  • Thomas R. Insel, M.D.
    Director
    National Institute of Mental Health
    National Institutes of Health
    Bethesda, Maryland

Federal Members

  • James F. Battey, M.D., Ph.D.
    Director
    National Institute on Deafness and Other Communication Disorders
    National Institutes of Health
    Bethesda, Maryland
  • Linda Birnbaum, Ph.D.
    Director
    National Institute of Environmental Health Sciences
    National Institutes of Health
    Research Triangle Park, North Carolina
  • Ellen W. Blackwell, M.S.W.
    Division of Community and Institutional Services
    Disabled and Elderly Health Programs Group
    Center for Medicaid and State Operations
    Centers for Medicare & Medicaid Services
    Baltimore, Maryland
  • Coleen Boyle, Ph.D.
    Acting Director
    National Center on Birth Defects and Developmental Disabilities
    Centers for Disease Control and Prevention
    Atlanta, Georgia
  • Larke N. Huang, Ph.D.
    Senior Advisor on Children
    Office of the Administrator
    Substance Abuse and Mental Health Services Administration
    Rockville, Maryland
  • Walter J. Koroshetz, M.D.
    Deputy Director
    National Institute of Neurological Disorder and Stroke
    National Institutes of Health
    Bethesda, Maryland
  • Henry Claypool
    Director
    Office on Disability
    U.S. Department of Health and Human Services
    Washington, DC
  • Francis S. Collins, M.D., Ph.D.
    Director
    National Institutes of Health
    Bethesda, Maryland
  • Alan E. Guttmacher, M.D.
    Acting Director
    Eunice Kennedy Shriver National Institute of Child Health and Human Development
    National Institutes of Health
    Bethesda, Maryland
  • Gail R. Houle, Ph.D.
    Associate Division Director
    Research-to-Practice Division
    Early Childhood Programs
    Office of Special Education Programs
    U.S. Department of Education
    Washington, DC

Public Members

  • Geraldine Dawson, Ph.D.
    Chief Science Officer
    Autism Speaks
    New York, New York
  • Gerald D. Fischbach, M.D.
    Scientific Director
    Simons Foundation Autism Research Initiative
    New York, New York
  • Lee Grossman
    President and CEO
    Autism Society of America
    Bethesda, Maryland
  • Yvette M. Janvier, M.D.
    Medical Director
    Children's Specialized Hospital
    Toms River, New Jersey
  • Christine M. McKee, J.D.
    Rockville, Maryland
  • Ari Ne'eman
    Founding President
    Autistic Self-Advocacy Network
    Washington, DC
  • Lyn Redwood, R.N., M.S.N.
    Co-Founder and Executive Director
    Coalition for Safe Minds
    Tyrone, Georgia
  • Denise D. Resnik
    Board Member and Co-Founder
    Southwest Autism Research and Resource Center
    Phoenix, Arizona
  • Stephen M. Shore, Ed.D.
    Executive Director
    Autism Spectrum Consulting and
    Assistant Professor of Special Education
    Adelphi University
    Newton, Massachusetts
  • Alison Tepper Singer, M.B.A.
    President
    Autism Science Foundation
    New York, New York
  • Marjorie Solomon, Ph.D., M.B.A.
    Assistant Clinical Professor
    University of California, Davis
    School of Medicine and
    M.I.N.D. Institute
    Sacramento, California

Office of Autism Research Coordination (OARC) Staff List

  • Della M. Hann, Ph.D.
    Acting Director
  • Susan A. Daniels, Ph.D.
    Deputy Director
  • Elizabeth M. Baden, Ph.D.
    Policy Analyst
  • Erin H. Bryant, M.J.
    Science Writer/Editor
  • Sara E. Dodson, Ph.D.
    AAAS Science & Technology
    Policy Fellow/Health Scientist
  • Nicole Jones
    Web Developer
  • Miguelina Perez
    Management Analyst

Copyright Information
All material appearing in this report is in the public domain and may be reproduced or copied. A suggested citation follows.

Suggested Citation
Interagency Autism Coordinating Committee (IACC). IACC Strategic Plan for Autism Spectrum Disorder (ASD) Research —2012 Update. December 2012. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: http://iacc.hhs.gov/strategic-plan/2012/index.shtml.


Appendices

 
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