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Summary of Advances Cover 2014

Summary of Advances

In Autism Spectrum Disorder Research


Articles Selected for the 2014 Summary of Advances

Question 1: When Should I Be Concerned?

  • Approaches to enhancing the early detection of autism spectrum disorders: a systematic review of the literature
  • Validation of the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F)

Question 2: How Can I Understand What Is Happening?

  • Synaptic, transcriptional and chromatin genes disrupted in autism
  • Behavioral and cognitive characteristics of females and males with autism in the Simons Simplex Collection
  • A higher mutational burden in females supports a “female protective model” in neurodevelopmental disorders
  • Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis
  • Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

Question 3: What Caused This to Happen and Can It Be Prevented?

  • Most genetic risk for autism resides with common variation
  • Prenatal SSRI use and offspring with autism spectrum disorder or developmental delay
  • The contribution of de novo coding mutations to autism spectrum disorder
  • The familial risk of autism
  • Vaccines are not associated with autism: an evidencebased meta-analysis of case-control and cohort studies

Question 4: Which Treatments and Interventions Will Help?

  • Caregiver-mediated intervention for low-resourced preschoolers with autism: an RCT
  • Parent-implemented social intervention for toddlers with autism: an RCT

Question 5: Where Can I Turn for Services?

  • Costs of autism spectrum disorders in the United Kingdom and the United States
  • Economic burden of childhood autism spectrum disorders

Question 6: What Does the Future Hold, Particularly for Adults?

  • A longitudinal examination of 10-year change in vocational and educational activities for adults with autism spectrum disorders

Question 7: What Other Infrastructure and Surveillance Needs Must Be Met?

  • Prevalence of autism spectrum disorder among children aged 8 years—autism and developmental disabilities monitoring network, 11 sites, United States, 2010
  • The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism
  • Potential impact of DSM5 criteria on autism spectrum disorder prevalence estimates

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